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Spastic paraplegia 4 (SPG4; often known as SPAST-HSP) is characterized by insidiously progressive bilateral reduce-limb gait spasticity. Much more than 50% of afflicted people have some weak point within the legs and impaired vibration feeling within the ankles.?? ????? ???? ??? ???? ?? ??? ? ?? ???? ??? ? ????. ?? ????? ??? ????? ??? ???? ?? ????

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